2-Cyanothiazole
Based on 1 Customer Validation
2-Cyanothiazole is a drug intermediate for synthesis of various active compounds.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 97.65%
- CAS No.: 1452-16-0
- 화학식: C4H2N2S
- 분자량:110.14
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보관:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
>40 μM
Compound: 59
|
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
|
[PMID: 35984756] |
| NCI-H522 | IC50 |
>40 μM
Compound: 59
|
Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based analysis
|
[PMID: 35984756] |
Chemical Information
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CAS No. 1452-16-0
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Appearance Solid-Liquid Mixture
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분자량 110.14
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화학식 C4H2N2S
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Color Light yellow to light brown
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SMILES
N#CC1=NC=CS1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 100 mg/mL (907.94 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (240 KB)
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SDS (647 KB)
- English - EN (647 KB)
- Français - FR (647 KB)
- Deutsch - DE (647 KB)
- Norwegian - NO (647 KB)
- Español - ES (647 KB)
- Swedish - SV (647 KB)
- Italian - IT (647 KB)
- Korean - KR (647 KB)
- Portuguese - PT (647 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 9.0794 mL | 45.3968 mL | 90.7935 mL | 226.9838 mL |
| 5 mM | 1.8159 mL | 9.0794 mL | 18.1587 mL | 45.3968 mL | |
| 10 mM | 0.9079 mL | 4.5397 mL | 9.0794 mL | 22.6984 mL | |
| 15 mM | 0.6053 mL | 3.0265 mL | 6.0529 mL | 15.1323 mL | |
| 20 mM | 0.4540 mL | 2.2698 mL | 4.5397 mL | 11.3492 mL | |
| 25 mM | 0.3632 mL | 1.8159 mL | 3.6317 mL | 9.0794 mL | |
| 30 mM | 0.3026 mL | 1.5132 mL | 3.0265 mL | 7.5661 mL | |
| 40 mM | 0.2270 mL | 1.1349 mL | 2.2698 mL | 5.6746 mL | |
| 50 mM | 0.1816 mL | 0.9079 mL | 1.8159 mL | 4.5397 mL | |
| 60 mM | 0.1513 mL | 0.7566 mL | 1.5132 mL | 3.7831 mL | |
| 80 mM | 0.1135 mL | 0.5675 mL | 1.1349 mL | 2.8373 mL | |
| 100 mM | 0.0908 mL | 0.4540 mL | 0.9079 mL | 2.2698 mL |