2′-Hydroxydihydrochalcone
Based on 1 Customer Validation
2′-Hydroxydihydrochalcone (Compound 2a) is an anti-inflammatory agent. 2′-Hydroxydihydrochalcone can be synthesized from the reduction of Flavone (HY-N2424).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.50%
- CAS No.: 3516-95-8
- 화학식: C15H14O2
- 분자량:226.27
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보관:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L929 | CC50 |
>200 μM
Compound: 27
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Cytotoxicity in mouse NCTC-929 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity in mouse NCTC-929 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
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[PMID: 31000155] |
Chemical Information
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CAS No. 3516-95-8
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Appearance <36°C Solid,>37°C Liquid
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분자량 226.27
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화학식 C15H14O2
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Color Off-white to light yellow
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SMILES
OC1=CC=CC=C1C(CCC2=CC=CC=C2)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 100 mg/mL (441.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
순도&문서
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.4195 mL | 22.0975 mL | 44.1950 mL | 110.4875 mL |
| 5 mM | 0.8839 mL | 4.4195 mL | 8.8390 mL | 22.0975 mL | |
| 10 mM | 0.4419 mL | 2.2097 mL | 4.4195 mL | 11.0487 mL | |
| 15 mM | 0.2946 mL | 1.4732 mL | 2.9463 mL | 7.3658 mL | |
| 20 mM | 0.2210 mL | 1.1049 mL | 2.2097 mL | 5.5244 mL | |
| 25 mM | 0.1768 mL | 0.8839 mL | 1.7678 mL | 4.4195 mL | |
| 30 mM | 0.1473 mL | 0.7366 mL | 1.4732 mL | 3.6829 mL | |
| 40 mM | 0.1105 mL | 0.5524 mL | 1.1049 mL | 2.7622 mL | |
| 50 mM | 0.0884 mL | 0.4419 mL | 0.8839 mL | 2.2097 mL | |
| 60 mM | 0.0737 mL | 0.3683 mL | 0.7366 mL | 1.8415 mL | |
| 80 mM | 0.0552 mL | 0.2762 mL | 0.5524 mL | 1.3811 mL | |
| 100 mM | 0.0442 mL | 0.2210 mL | 0.4419 mL | 1.1049 mL |
2′-Hydroxydihydrochalcone Related Classifications
HY-W012308 Related Classifications
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