7-Methyluric acid
Based on 1 Customer Validation
7-Methyluric acid is a methylated purine metabolite of Theobromine (HY-N0138) and Caffeine. 7-Methyluric acid is a substrate of OAT1 (SLC22A6) and OAT3 (SLC22A8). 7-Methyluric acid is not transported by OATP1B1, OATP1B3, OCT2, MATE1, or P-glycoprotein. 7-Methyluric acid can be used in studies on urolithiasis.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.9%
- CAS No.: 612-37-3
- 화학식: C6H6N4O3
- 분자량:182.14
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 612-37-3
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Appearance Solid
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분자량 182.14
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화학식 C6H6N4O3
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Color White to off-white
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SMILES
O=C(NC(N1)=C2N(C)C1=O)NC2=O
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Structure Classification
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Initial Source
rat's urine
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 20 mg/mL (109.81 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
순도&문서
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[2]. Safranow K, et al. Methylated purines in urinary stones. Clinical chemistry. 2005 Aug;51(8):1493-8.
[5]. Burg AW. Physiological disposition of caffeine. Drug metabolism reviews. 1975 Jan 1;4(2):199-228.
[10]. Damen J. Metabolome of healthy and unhealthy dietary patterns.
[12]. Aldridge A J. The effect of age and species on the metabolism of caffeine[J]. 1979.
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.4903 mL | 27.4514 mL | 54.9028 mL | 137.2571 mL |
| 5 mM | 1.0981 mL | 5.4903 mL | 10.9806 mL | 27.4514 mL | |
| 10 mM | 0.5490 mL | 2.7451 mL | 5.4903 mL | 13.7257 mL | |
| 15 mM | 0.3660 mL | 1.8301 mL | 3.6602 mL | 9.1505 mL | |
| 20 mM | 0.2745 mL | 1.3726 mL | 2.7451 mL | 6.8629 mL | |
| 25 mM | 0.2196 mL | 1.0981 mL | 2.1961 mL | 5.4903 mL | |
| 30 mM | 0.1830 mL | 0.9150 mL | 1.8301 mL | 4.5752 mL | |
| 40 mM | 0.1373 mL | 0.6863 mL | 1.3726 mL | 3.4314 mL | |
| 50 mM | 0.1098 mL | 0.5490 mL | 1.0981 mL | 2.7451 mL | |
| 60 mM | 0.0915 mL | 0.4575 mL | 0.9150 mL | 2.2876 mL | |
| 80 mM | 0.0686 mL | 0.3431 mL | 0.6863 mL | 1.7157 mL | |
| 100 mM | 0.0549 mL | 0.2745 mL | 0.5490 mL | 1.3726 mL |
7-Methyluric acid Related Classifications
HY-W016415 Related Classifications
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