CRAC intermediate 1
Based on 1 Customer Validation
CRAC intermediate 1 is a key intermediate that can be used in synthesis of a series of CRAC channel inhibitors.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.46%
- CAS No.: 1249343-86-9
- 화학식: C10H7F2N3O
- 분자량:223.18
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
CRAC intermediate 1 (intermediate 9) can be used for synthesis of CARC inhibitors that can be useful in the treatment of allergic, inflammatory or autoimmune diseases[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1249343-86-9
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Appearance Solid
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분자량 223.18
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화학식 C10H7F2N3O
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Color White to off-white
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SMILES
O=C(C1=C(F)C=CC=C1F)NC2=NNC=C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
용액&용해도
DMSO : ≥ 50 mg/mL (224.03 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4807 mL | 22.4034 mL | 44.8069 mL | 112.0172 mL |
| 5 mM | 0.8961 mL | 4.4807 mL | 8.9614 mL | 22.4034 mL | |
| 10 mM | 0.4481 mL | 2.2403 mL | 4.4807 mL | 11.2017 mL | |
| 15 mM | 0.2987 mL | 1.4936 mL | 2.9871 mL | 7.4678 mL | |
| 20 mM | 0.2240 mL | 1.1202 mL | 2.2403 mL | 5.6009 mL | |
| 25 mM | 0.1792 mL | 0.8961 mL | 1.7923 mL | 4.4807 mL | |
| 30 mM | 0.1494 mL | 0.7468 mL | 1.4936 mL | 3.7339 mL | |
| 40 mM | 0.1120 mL | 0.5601 mL | 1.1202 mL | 2.8004 mL | |
| 50 mM | 0.0896 mL | 0.4481 mL | 0.8961 mL | 2.2403 mL | |
| 60 mM | 0.0747 mL | 0.3734 mL | 0.7468 mL | 1.8670 mL | |
| 80 mM | 0.0560 mL | 0.2800 mL | 0.5601 mL | 1.4002 mL | |
| 100 mM | 0.0448 mL | 0.2240 mL | 0.4481 mL | 1.1202 mL |
CRAC intermediate 1 Related Classifications
HY-20587 Related Classifications
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