F 16915
Based on 1 Customer Validation
F 16915, a Docosahexaenoic Acid (DHA, HY-B2167) derivative, is a potent pro-agent of DHA. F 16915 can prevent heart failure-induced atrial fibrillation.
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- Purity : 98.16%
- CAS No.: 92510-91-3
- 화학식: C28H37NO2
- 분자량:419.60
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보관:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vivo
F 16915 (1-5 g/day for 4 weeks) significantly reduces the infarct size and prevents the left ventricular free wall thinning[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats (220-300 g) with heart failure induced by occlusion of left descending coronary artery and 2 months reperfusion[1]
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Dosage:100 mg/kg
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Administration:Daily oral gavage
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Result:Reduced the infarct size.
Prevented the left ventricular free wall thinning.
Reduced the de-phosphorylation of connexin43 from atria tissue.
Chemical Information
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CAS No. 92510-91-3
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Appearance Oil
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분자량 419.60
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화학식 C28H37NO2
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Color Colorless to light yellow
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SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(OCC1=CC=CN=C1)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
In Vitro:
DMSO : ≥ 100 mg/mL (238.32 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
순도&문서
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3832 mL | 11.9161 mL | 23.8322 mL | 59.5806 mL |
| 5 mM | 0.4766 mL | 2.3832 mL | 4.7664 mL | 11.9161 mL | |
| 10 mM | 0.2383 mL | 1.1916 mL | 2.3832 mL | 5.9581 mL | |
| 15 mM | 0.1589 mL | 0.7944 mL | 1.5888 mL | 3.9720 mL | |
| 20 mM | 0.1192 mL | 0.5958 mL | 1.1916 mL | 2.9790 mL | |
| 25 mM | 0.0953 mL | 0.4766 mL | 0.9533 mL | 2.3832 mL | |
| 30 mM | 0.0794 mL | 0.3972 mL | 0.7944 mL | 1.9860 mL | |
| 40 mM | 0.0596 mL | 0.2979 mL | 0.5958 mL | 1.4895 mL | |
| 50 mM | 0.0477 mL | 0.2383 mL | 0.4766 mL | 1.1916 mL | |
| 60 mM | 0.0397 mL | 0.1986 mL | 0.3972 mL | 0.9930 mL | |
| 80 mM | 0.0298 mL | 0.1490 mL | 0.2979 mL | 0.7448 mL | |
| 100 mM | 0.0238 mL | 0.1192 mL | 0.2383 mL | 0.5958 mL |
F 16915 Related Classifications
HY-19886 Related Classifications
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