NGR peptide Trifluoroacetate
Based on 1 publication(s) in Google Scholar
NGR peptide Trifluoroacetatecontaining the Asn-Gly-Arg (NGR) motif. NGR peptide Trifluoroacetate binds to APN/CD13. NGR peptide Trifluoroacetate is directly conjugated to imaging agents that can be used for tumor imaging.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 98.91%
- 화학식: C22H37F3N10O10S2
- 분자량:722.72
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보관:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- Protocol
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) NGR peptide Trifluoroacetate
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Biological Activity
제품 설명
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CD13 |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:4-6 weeks, BALB/c nude mice (HepG2 tumor model)[2]
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Dosage:20 mg/kg
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Administration:I.v.
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Result:Blocked the tumor uptake for 99mTc-NGR.
Chemical Information
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Appearance Solid
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분자량 722.72
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화학식 C22H37F3N10O10S2
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Color White to off-white
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Sequence
Cys-Asn-Gly-Arg-Cys-Gly
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Sequence Shortening
CNGRCG
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Mater
Dismantlable Coronated Nanoparticles for Coupling the Induction and Perception of Immunogenic Cell Death. [Abstract]2024 Jul;36(27):e2313097. PMID: 38643386
용액&용해도
In Vitro:
H2O : ≥ 100 mg/mL (138.37 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (138.37 mM); Clear solution; Need ultrasonic
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
순도&문서
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Wang RE, et al. Development of NGR peptide-based agents for tumor imaging. Am J Nucl Med Mol Imaging. 2011;1(1):36-46. [Content Brief]
[2]. Ma W, et al. Biodistribution and SPECT imaging study of (99m)Tc labeling NGR peptide in nude mice bearing human HepG2 hepatoma. Biomed Res Int. 2014;2014:618096. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.3837 mL | 6.9183 mL | 13.8366 mL | 34.5915 mL |
| 5 mM | 0.2767 mL | 1.3837 mL | 2.7673 mL | 6.9183 mL | |
| 10 mM | 0.1384 mL | 0.6918 mL | 1.3837 mL | 3.4592 mL | |
| 15 mM | 0.0922 mL | 0.4612 mL | 0.9224 mL | 2.3061 mL | |
| 20 mM | 0.0692 mL | 0.3459 mL | 0.6918 mL | 1.7296 mL | |
| 25 mM | 0.0553 mL | 0.2767 mL | 0.5535 mL | 1.3837 mL | |
| 30 mM | 0.0461 mL | 0.2306 mL | 0.4612 mL | 1.1531 mL | |
| 40 mM | 0.0346 mL | 0.1730 mL | 0.3459 mL | 0.8648 mL | |
| 50 mM | 0.0277 mL | 0.1384 mL | 0.2767 mL | 0.6918 mL | |
| 60 mM | 0.0231 mL | 0.1153 mL | 0.2306 mL | 0.5765 mL | |
| 80 mM | 0.0173 mL | 0.0865 mL | 0.1730 mL | 0.4324 mL | |
| 100 mM | 0.0138 mL | 0.0692 mL | 0.1384 mL | 0.3459 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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