SA72
SA72 is a highly selective fatty acid amide hydrolase (FAAH) inhibitor.
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- CAS No.: 934809-60-6
- 화학식: C21H26N2O6
- 분자량:402.44
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
IC50 & Target
Fatty acid amide hydrolase (FAAH)[1]
In Vitro
Fatty acid amide hydrolase (FAAH) is the primary regulator of several bioactive lipid amides including anandamide. Inhibitors of FAAH are potentially useful for the treatment of pain, anxiety, depression, and other nervous system disorders. However, FAAH inhibitors must display selectivity for this enzyme relative to the numerous other serine hydrolases present in the human proteome in order to be therapeutically acceptable. SA-72 is also a carbamate inhibitor. However, SA-72 shows exceptional selectivity for FAAH. Tested carboxylesterases are not off-targets for SA-72. SA-72 does not have major effects on the level of carboxylesterase activities in liver microsomes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 934809-60-6
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분자량 402.44
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화학식 C21H26N2O6
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SMILES
O=C(OCC(N)=O)NCCCC1OCC(C2=C3C=CC(OC)=CC3=CC=C2)CO1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)