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Cat. No.: HY-100174

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W-2429

(Synonyms: NSC294836)

W-2429 (NSC294836) is considerably more effective than acetylsalicylic acid in inhibiting carrageenan-induced edema and in reducing brewer's yeast-induced fever in rats.

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CAS No.: 37795-69-0
화학식: C₁₀H₈N₂O₂
분자량:188.18

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

W-2429 Chemical Structure

CAS No.: 37795-69-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

W-2429 (NSC294836) is considerably more effective than acetylsalicylic acid in inhibiting carrageenan-induced edema and in reducing brewer's yeast-induced fever in rats^[2].

In Vivo

W-2429 is a non-narcotic analgesic agent. Treatment with W-2429 is well tolerated by rats as well as dogs. In the dog, the only signs of toxicity observed are decreased appetite and salivation at 100 mg/kg/day W-2429. No other significant evidence of physical, chemical, gross or histopathologic change is observed^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 37795-69-0
분자량 188.18
화학식 C₁₀H₈N₂O₂
SMILES

O=C1N(OCC2)C2=NC3=C1C=CC=C3
Synonyms

NSC294836
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Banerjee BN, et al. Toxicological investigation of 2,3-dihydro-9H-isoxazolo[3,2-b]quinazolin-9-one (W-2429). Acuteand subacute toxicity in mice, rats and dogs. Arzneimittelforschung. 1977;27(4):793-801. [Content Brief]

[2]. Reisner DB, Ludwig BJ, Simon E, Dejneka T, Sofia RD. 2,3-Dihydro-9H-isoxazolo[3,2-b]quinazolin-9-ones and 3,4-dihydro-(1,2)-oxazino [3,2-b]quinazolin-10(2H)-ones. Arzneimittelforschung. 1977;27(4):766-770. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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