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United States

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Cat. No.: HY-100258

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Y-9738

Y-9738 is a hypolipidemic agent.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 59399-41-6
화학식: C₁₅H₁₆ClNO₄
분자량:309.74

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Y-9738 Chemical Structure

CAS No.: 59399-41-6

사이즈

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Y-9738 is a hypolipidemic agent.

In Vivo

Y-9738 is a hypolipidemic agent. At 100 mg/kg Y-9738 lowers the cholesterol level by 36% and clearly diminishes the intensity of the β-lipoprotein band with a tendency for the α-lipoprotein band to be intensified. Y-9738 causes a dose-dependent decrease in serum cholesterol, triglyceride and heparin-precipitable β-lipoprotein cholesterol. Furthermore, Y-9738 reduces the intensity of the β-lipoprotein band shown by electrophoresis, and increases that of the α-lipoprotein band^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 59399-41-6
분자량 309.74
화학식 C₁₅H₁₆ClNO₄
SMILES

O=C(OCC)CC1=C(OCC)OC(C2=CC=C(Cl)C=C2)=N1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocol

Animal Administration^[1]

Male Sprague-Dawley rats are used in this work. Rats (140 to 180 g) are fed a high cholesterol diet for 10 days. This diet contains 1% cholesterol, 0.2% sodium cholate and 5% olive oil. Y-9738 is orally administered to the animals once a day throughout the experimental period. All animals are starved overnight (about 20 h) after the last treatment and sacrificed by carotid incision. Blood and liver are collected for lipid analysis^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kobayakawa T, et al. Experimental hyper-beta-lipoproteinemia and its amelioration by a novel hypolipidemic agent. Atherosclerosis. 1978 Jul;30(3):219-25. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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