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Cat. No.: HY-155183

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A3AR agonist 1

A3AR agonist 1 (Compound 12) is an A3AR agonist (K_i: 25.8 nM). A3AR agonist 1 stimulates β-arrestin2 recruitment, with an EC₅₀ value of 5.17 nM. A3AR agonist 1 can be used for research of inflammatory diseases, ischemia, cancer, neuropathic pain, liver diseases, etc.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₈H₃₄N₆O₆
분자량:550.61

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

A3AR agonist 1 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Adenosine Receptor Isoforms :

Chemical Information

분자량 550.61
화학식 C₂₈H₃₄N₆O₆
SMILES

CNC([C@]12[C@@H](O)[C@@H](O)[C@H](N3C=NC4=C3N=C5N=C4NCCC6=CC(OCC/C=C/CCO5)=C(OC)C=C6)[C@H]1C2)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dilip K. Tosh, et al. First Potent Macrocyclic A3 Adenosine Receptor Agonists Reveal G-Protein and 尾-Arrestin2 Signaling Preferences. ACS Pharmacol. Transl. Sci. 2023, 6, 9, 1288鈥?305.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
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Chemical Information
순도&문서
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A3AR agonist 1

All Adenosine Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

A3AR agonist 1 Related Classifications

HY-155183 Related Classifications