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Cat. No.: HY-122019

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ABD56

ABD56 is a compound that induces osteoclast apoptosis and has the activity of inhibiting osteoclast formation and inducing apoptosis. ABD56 can inhibit osteoclast formation and induce apoptosis, and its mechanism is related to the inhibition of NFκB and ERK pathways.

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CAS No.: 521294-19-9
화학식: C₁₇H₁₈O₃
분자량:270.32

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

ABD56 Chemical Structure

CAS No.: 521294-19-9

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All NF-κB Isoforms :

All ERK Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Hepatocyte	IC₅₀	>200 μM Compound: 67, ABD56	Effect on apoptosis of hepatocyte Effect on apoptosis of hepatocyte	[PMID: 17149877]
Osteoblast	IC₅₀	>100 μM Compound: 67, ABD56	Effect on apoptosis of osteoblast Effect on apoptosis of osteoblast	[PMID: 17149877]
Osteoclast	IC₅₀	9 μM Compound: 67, ABD56	Inhibition of mouse osteoclast survival Inhibition of mouse osteoclast survival	[PMID: 17149877]

Chemical Information

CAS No. 521294-19-9
분자량 270.32
화학식 C₁₇H₁₈O₃
SMILES

O=C(OCCCCO)C1=CC=C(C=C1)C2=CC=CC=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. ABD56 causes osteoclast apoptosis by inhibiting the NFkappaB and ERK pathways [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
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상품명:
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ABD56

All NF-κB Isoforms

All ERK Isoforms