AChE-IN-115
AChE-IN-115 is an acetylcholinesterase (AChE) inhibitor. AChE-IN-115 forms stable complexes with AChE from Spodoptera litura (tobacco cutworm) and Tribolium castaneum (red flour beetle). AChE-IN-115 exhibits insecticidal activity.
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- 화학식: C28H20N4O3
- 분자량:460.48
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
[1]|
AChE |
In Vivo
AChE-IN-115 (31.25-1000 ppm; contact; 24-72 h) exhibits strong activity against the red flour beetle (Tribolium castaneum)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Spodoptera littoralis 4th instar larvae[1]
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Dosage:15.62, 31.25, 62.5, 125, 250, 500, 1000 ppm
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Administration:24, 48, 72 h
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Result:Exhibited an LC50 value of 49.57 ppm at 72 h post-treatment.
Caused 0% mortality at 24 h (15.62 ppm), 0% mortality at 24 h (31.25 ppm), 20.00% mortality at 24 h (62.5 ppm), 73.33% mortality at 24 h (125 ppm), 80.00% mortality at 24 h (250 ppm), 86.67% mortality at 24 h (500 ppm), 100.00% mortality at 24 h (1000 ppm).
Caused 0% mortality at 48 h (15.62 ppm), 6.67% mortality at 48 h (31.25 ppm), 40.00% mortality at 48 h (62.5 ppm), 60.00% mortality at 48 h (125 ppm), 100.00% mortality at 48 h (250-1000 ppm).
Caused 6.67% mortality at 72 h (15.62 ppm), 13.33% mortality at 72 h (31.25 ppm), 60.00% mortality at 72 h (62.5 ppm), 100.00% mortality at 72 h (125-1000 ppm).
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Animal Model:Tribolium castaneum (adults)[1]
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Dosage:15.62, 31.25, 62.5, 125, 250, 500, 1000
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Administration:24, 48, 72 h
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Result:Exhibited an LC50 value of 79.58 ppm at 72 h post-treatment.
Caused 13.33% mortality at 24 h (31.25 ppm), 26.67% mortality at 24 h (62.5 ppm), 33.33% mortality at 24 h (125 ppm), 53.33% mortality at 24 h (250 ppm), 60.00% mortality at 24 h (500 ppm), 80.00% mortality at 24 h (1000 ppm).
Caused 20.00% mortality at 48 h (31.25 ppm), 33.33% mortality at 48 h (62.5 ppm), 46.67% mortality at 48 h (125 ppm), 66.67% mortality at 48 h (250 ppm), 73.33% mortality at 48 h (500 ppm), 93.33% mortality at 48 h (1000 ppm).
Caused 26.67% mortality at 72 h (31.25 ppm), 40.00% mortality at 72 h (62.5 ppm), 66.67% mortality at 72 h (125 ppm), 73.33% mortality at 72 h (250 ppm), 93.33% mortality at 72 h (500 ppm), 100.00% mortality at 72 h (1000 ppm).
Chemical Information
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분자량 460.48
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화학식 C28H20N4O3
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SMILES
O=C(NC1=CC=C(OC)C=C1)/C(C#N)=C/C2=CN(C3=CC=CC=C3)N=C2C4=CC5=CC=CC=C5O4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE-IN-115 Related Classifications
HY-183066 Related Classifications
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