AG 538
Based on 1 Customer Validation
AG 538 is a potent, competitive inhibitor of IGF-1 receptor kinase, with an IC50 of 400 nM.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.99%
- CAS No.: 133550-18-2
- 화학식: C16H11NO5
- 분자량:297.26
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
4 x 10-1 μM
Compound: 149
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Inhibition of EGFR in human A431 cells
Inhibition of EGFR in human A431 cells
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[PMID: 1479375] |
Chemical Information
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CAS No. 133550-18-2
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Appearance Solid
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분자량 297.26
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화학식 C16H11NO5
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Color Light yellow to yellow
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SMILES
N#C/C(C(C1=CC=C(O)C(O)=C1)=O)=C\C2=CC=C(O)C(O)=C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 100 mg/mL (336.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3641 mL | 16.8203 mL | 33.6406 mL | 84.1015 mL |
| 5 mM | 0.6728 mL | 3.3641 mL | 6.7281 mL | 16.8203 mL | |
| 10 mM | 0.3364 mL | 1.6820 mL | 3.3641 mL | 8.4101 mL | |
| 15 mM | 0.2243 mL | 1.1214 mL | 2.2427 mL | 5.6068 mL | |
| 20 mM | 0.1682 mL | 0.8410 mL | 1.6820 mL | 4.2051 mL | |
| 25 mM | 0.1346 mL | 0.6728 mL | 1.3456 mL | 3.3641 mL | |
| 30 mM | 0.1121 mL | 0.5607 mL | 1.1214 mL | 2.8034 mL | |
| 40 mM | 0.0841 mL | 0.4205 mL | 0.8410 mL | 2.1025 mL | |
| 50 mM | 0.0673 mL | 0.3364 mL | 0.6728 mL | 1.6820 mL | |
| 60 mM | 0.0561 mL | 0.2803 mL | 0.5607 mL | 1.4017 mL | |
| 80 mM | 0.0421 mL | 0.2103 mL | 0.4205 mL | 1.0513 mL | |
| 100 mM | 0.0336 mL | 0.1682 mL | 0.3364 mL | 0.8410 mL |
AG 538 Related Classifications
HY-135436 Related Classifications
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