Anticancer agent 254
Based on 1 Customer Validation
Anticancer agent 254 (compound 10) is a dichloroacetic acid-loaded compound with enhanced antitumor activity against leukemia cells in vitro and better stability in vivo, and can be considered for preclinical evaluation of cancer inhibition.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 95.62%
- CAS No.: 1841421-67-7
- 화학식: C12H18Cl6N4O3
- 분자량:479.01
-
보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
0.34 mM
Compound: 10
|
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 26653539] |
| JVM-2 | IC50 |
0.41 mM
Compound: 10
|
Cytotoxicity against human JVM2 cells after 48 hrs by MTT assay
Cytotoxicity against human JVM2 cells after 48 hrs by MTT assay
|
[PMID: 26653539] |
| Maver1 | IC50 |
0.55 mM
Compound: 10
|
Cytotoxicity against human Maver1 cells after 48 hrs by MTT assay
Cytotoxicity against human Maver1 cells after 48 hrs by MTT assay
|
[PMID: 26653539] |
| PBMC | IC50 |
1.26 mM
Compound: 10
|
Cytotoxicity against human PBMC cells after 48 hrs by MTT assay
Cytotoxicity against human PBMC cells after 48 hrs by MTT assay
|
[PMID: 26653539] |
Chemical Information
-
CAS No. 1841421-67-7
-
Appearance Solid
-
분자량 479.01
-
화학식 C12H18Cl6N4O3
-
Color White to off-white
-
SMILES
ClC(C(NCCN(CCNC(C(Cl)Cl)=O)CCNC(C(Cl)Cl)=O)=O)Cl
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
순도&문서
-
Data Sheet (265 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)