Anticancer agent 272
Anticancer agent 272 (Compound 2) is an anticancer agent. Anticancer agent 272 has significant anti-bladder cancer cell (T-24) activity (IC50: 2.81 μM). Anticancer agent 272 consumes glutathione (GSH) through Fenton-like reaction, produces reactive oxygen species (ROS) and hydroxyl radicals (?OH), and induces apoptosis and ferroptosis. Anticancer agent 272 can enhance chemodynamic therapy (CDT) and promote tumor cell death through mitochondrial dysfunction and autophagy. Anticancer agent 272 has potential in the study of bladder cancer.
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- 화학식: C26H34Br2Cl4Cu2N8
- 분자량:887.31
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Chemical Information
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분자량 887.31
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화학식 C26H34Br2Cl4Cu2N8
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SMILES
BrC1=CN=C(N2[N]([Cu+2]34([Cl-][Cu+2]5([Cl-])([Cl-]4)[N](N6C7=NC=C(C=[N]75)Br)=C(C=C6C(C)C)C(C)C)[Cl-])=C(C=C2C(C)C)C(C)C)[N]3=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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