Anticancer agent 87
Anticancer agent 87 is a spirooxindole-furan derivative with anticancer activity. Anticancer agent 87 can be used for the research of breast adenocarcinoma and human liver cancer.
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- 화학식: C30H21BrCl2N2O3S
- 분자량:640.37
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
In Vitro
Anticancer agent 87 (Compound 6f) potently inhibits the viability of MCF7 breast adenocarcinoma cells with an IC50 of 10.3 μM/mL[1].
Anticancer agent 87 potently inhibits the viability of HepG2 liver carcinoma cells with an IC50 of 3.5 μM/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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분자량 640.37
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화학식 C30H21BrCl2N2O3S
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SMILES
O=C1NC2=C(C=CC(Cl)=C2)[C@@]13N4CSCC4[C@@H](C5=CC=C(C6=CC=CC=C6Cl)O5)[C@@H]3C(C7=CC=C(Br)C=C7)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)