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Cat. No.: HY-151588

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Anticancer agent 90

Anticancer agent 90 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity. Anticancer agent 90 has high inhibition against the two cell line from ovarian cancer (OVCAR-4), renal cancer (A498).

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CAS No.: 2977251-03-7
화학식: C₃₃H₃₂N₂O₁₀S₃
분자량:712.81

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (282 KB)

Anticancer agent 90 Chemical Structure

CAS No.: 2977251-03-7

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

Anticancer agent 90 (compound 6d) (0.01 mM; 24 h) has low cytotoxicity, shows high inhibition against two cell lines, SK-MEL-5, OVCAR-4^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cell lines
Concentration:

0-200 μg/mL
Incubation Time:

24 hours
Result:

Showed nontoxic under the doses of 100 μg/mL against FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cells, respectively.

Cell Viability Assay^[1]

Cell Line:

SK-MEL-5, OVCAR-4, and A498
Concentration:

0.01 mM
Incubation Time:

24 hours
Result:

Inhibited SK-MEL-5 and OVCAR-4 cell viability by 30.64% and 30.71%, respectively.

Related Protocols :

Subcutaneous Cell-Line-Derived Xenograft

Chemical Information

CAS No. 2977251-03-7
분자량 712.81
화학식 C₃₃H₃₂N₂O₁₀S₃
SMILES

[H][C@]1([C@@H]([C@H]([C@@H](O[C@@H]1COC(C)=O)SC2=C(C(N)=C(S2)C(C3=CC=C(C=C3)C)=O)C4=NC5=C(S4)C=CC=C5)OC(C)=O)OC(C)=O)OC(C)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (282 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Azzam et al. Novel Thiophene Thioglycosides Substituted with the Benzothiazole Moiety: Synthesis, Characterization, Antiviral and Anticancer Evaluations, and NS3/4A and USP7 Enzyme Inhibitions. ACS Omega. 2022 Sep 29;7(40):35656-35667. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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