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Cat. No.: HY-117457

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BPIC

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1444382-92-6
화학식: C₂₇H₂₀N₂O₅
분자량:452.46

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

BPIC Chemical Structure

CAS No.: 1444382-92-6

사이즈

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals^[1].

All DNA/RNA Synthesis Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
CCRF S-180	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HeLa	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HepG2	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HL-60	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
HT-29	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
K562	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]
SH-SY5Y	IC₅₀	0.96 μM Compound: BPIC	Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25648297]

Chemical Information

CAS No. 1444382-92-6
분자량 452.46
화학식 C₂₇H₂₀N₂O₅
SMILES

O=C(C1=C(O)C=CC(C2=NC(C(OCC3=CC=CC=C3)=O)=CC4=C2NC5=C4C=CC=C5)=C1)OC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shan Li, et al. BPIC: A novel anti-tumor lead capable of inhibiting inflammation and scavenging free radicals. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1146-50. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
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BPIC

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

BPIC Related Classifications

HY-117457 Related Classifications