BU72
BU72 is a highly potent and long-acting agonist of μ and κ opioid receptors, and also has a partial agonist effect on δ opioid receptors (EC50 values are 0.054, 0.033, and 0.58 nM, respectively). BU72 has a strong and long-lasting analgesic effect, which is mainly mediated by μ opioid receptors. BU72 has a long-lasting activity and can partially reverse the analgesic effect of morphine. BU72 can be used in the study of opioid dependence.
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- CAS No.: 173265-76-4
- 화학식: C28H32N2O2
- 분자량:428.57
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Opioid Receptor Isoforms
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Biological Activity
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μ Opioid Receptor/MOR 0.054 nM (EC50) |
κ Opioid Receptor/KOR 0.033 nM (EC50) |
δ Opioid Receptor/DOR 0.58 nM (EC50) |
Chemical Information
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CAS No. 173265-76-4
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분자량 428.57
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화학식 C28H32N2O2
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SMILES
CO[C@@]12[C@](N[C@@H]3C4=CC=CC=C4)([H])[C@@](C5=CC(O)=CC=C5C[C@@]6([H])N7C)(CC7)C6(C=C2)CC13C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)