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Cat. No.: HY-125748

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CBM-301940

Name: CBM-301940
Brand: MedChemExpress
SKU: HY-125748
Price: 410.00 USD
Availability: InStock
Rating: 5 (1 reviews)

1 Cited Publications

고객리뷰

Based on 1 publication(s) in Google Scholar

CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC₅₀ value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity : 99.4%
CAS No.: 902146-11-6
화학식: C₁₅H₂₀F₆N₂O₅
분자량:422.32

보관:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

CBM-301940 Chemical Structure

CAS No.: 902146-11-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
Publications (1)
Protocol (1)
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC₅₀ value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases^[1].

IC₅₀ & Target

Malonate CoA Decarboxylase (MCD)^[1]

Chemical Information

CAS No. 902146-11-6
Appearance Solid
분자량 422.32
화학식 C₁₅H₂₀F₆N₂O₅
Color White to light yellow
SMILES

CC(NC(C1=NOC(C(C(F)(F)F)(O)C(F)(F)F)C1)=O)CC(OC(C)(C)C)=O
선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Publications (1)

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Journal Impact Factor

Cancer Res

FASN Inhibition Enhances the Efficacy of Chemotherapy in Colorectal Cancer by Inhibiting the DNA Damage Response. [Abstract]

2026 Feb 9. PMID: 41661672

Protocol

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cheng JF, et al. Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents. J Med Chem. 2006 Jul 13;49(14):4055-8. doi: 10.1021/jm0605029. PMID: 16821767. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

CBM-301940

1 Cited Publications

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
Publications (1)
Protocol
순도&문서
References

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CBM-301940

Publications Citing Use of MedChemExpress (MCE) CBM-301940