CDC20-IN-2
CDC20-IN-2 (14c), a Cdc20 inhibitor (KD: 7.65 μM), causes G2/M phase arrest and promotes DNA damage accumulation. CDC20-IN-2 (14c) stabilizes key substrates such as Cyclin B1 and Bim, leading to enhanced apoptosis and suppression of tumor cell proliferation and migration.
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- CAS No.: 3080812-16-1
- 화학식: C21H15Cl4F6N7O3S
- 분자량:701.26
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
CDC20-IN-2 (14c) exhibits IC50 values of 3.28 μM and 23.86 μM in MDA-MB-231 and MCF 10A cells, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3080812-16-1
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분자량 701.26
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화학식 C21H15Cl4F6N7O3S
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SMILES
FC(F)(F)C1=CC=C(NC2=CC(Cl)=NC(NC(NC(OCCNC(C3=CN=C(C(F)(F)F)S3)=O)=O)C(Cl)(Cl)Cl)=N2)C=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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