Chlorophyll b
Based on 1 Customer Validation
Chlorophyll b is an orally active tetrapyrrole derivative and pigment. Chlorophyll b can be obtained from photosynthetic organisms such as plants and algae. Chlorophyll b acts as a hydrogen donor and increases Glutathione levels. Chlorophyll b has antioxidant activity and functionally replaces chlorophyll a in photosystem II to participate in photosynthesis. Chlorophyll b reduces Cisplatin (HY-17394)-induced DNA damage, chromosome instability, and oxidative stress. Chlorophyll b is mainly used in the study of plant photosynthesis mechanism.
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- Purity: 95%
- CAS No.: 519-62-0
- 화학식: C55H71MgN4O6+
- 분자량:908.48
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보관:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
Chlorophyll b can serve as the major pigment in functional photosystem II complexes of cyanobacteria when introduced into a photosystem I-less strain of Synechocystis sp. PCC 6803 along with lhcb encoding light-harvesting complex (LHC)II from pea[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chlorophyll b (0.5 mg/kg; gavage; daily; 13 days) combined with lutein shows antigenotoxic and antimutagenic effects as well as prevents Cisplatin-induced GSH depletion in peripheral blood cells in mice[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female and male albino Swiss mice (Mus musculus) (both genders, approximately 30 g, 7-8 weeks old)[3]
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Dosage:0.5 mg/kg body weight
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Administration:Administered daily by gavage for 13 consecutive days
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Result:Presented antigenotoxic and antimutagenic effects in different cell types of mice, such as peripheral blood, bone marrow, liver, and kidney cells.
Prevented the glutathione depletion induced by cisplatin in peripheral blood cells, maintaining the glutathione concentration at a level similar to the control group.
Had no significant effect on catalase activity.
Chemical Information
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CAS No. 519-62-0
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Appearance Solid
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분자량 908.48
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화학식 C55H71MgN4O6+
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Color Green to dark green
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SMILES
C=CC1=C(C)C2=CC3=NC(=C4[C@H](C(=O)C5=C(C)C(=CC6=C(CC)C(=CO)C(=N6)C=C1[N-]2)N=C54)C(=O)OC)[C@@H](CCC(=O)OC/C=C(\C)/CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@@H]3C.[Mg+2]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
Ethanol : 10 mg/mL (11.01 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Xu H, et al. Chlorophyll b can serve as the major pigment in functional photosystem II complexes of cyanobacteria. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):14168-73. [Content Brief]
[2]. Serpeloni JM, et al. An evaluation, using the comet assay and the micronucleus test, of the antigenotoxic effects of chlorophyll b in mice. Mutat Res. 2011 Oct 9;725(1-2):50-6. [Content Brief]
[3]. Serpeloni JM, et al. Effects of lutein and chlorophyll b on GSH depletion and DNA damage induced by cisplatin in vivo. Hum Exp Toxicol. 2013 Aug;32(8):828-36. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 1.1007 mL | 5.5037 mL | 11.0074 mL | 27.5185 mL |
| 5 mM | 0.2201 mL | 1.1007 mL | 2.2015 mL | 5.5037 mL | |
| 10 mM | 0.1101 mL | 0.5504 mL | 1.1007 mL | 2.7518 mL |
Chlorophyll b Related Classifications
HY-W127709 Related Classifications
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