Chondrillasterol
Chondrillasterol is a sterol that can be isolated from Vernonia adoensis. Chondrillasterol exhibits antibacterial activity. Chondrillasterol inhibits growth of Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Chondrillasterol inhibits formation of bacterial biofilms. Chondrillasterol can be used for the research of bacterial infections.
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- CAS No.: 481-17-4
- 화학식: C29H48O
- 분자량:412.70
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chondrillasterol (12.5-100 μg/mL; 20 h) inhibits the growth of Pseudomonas aeruginosa by 65%, Klebsiella pneumoniae by 38%, and Staphylococcus aureus by 25%[1].
Chondrillasterol (50-100 μg/mL; 10 min) does not cause significant nucleic acid leakage from Pseudomonas aeruginosa[1].
Chondrillasterol (0.4-100 μg/mL; 72 h) completely inhibits biofilm formation by Pseudomonas aeruginosa at 100 μg/mL, and causes significant inhibition at concentrations as low as 6.3 μg/mL[1].
Chondrillasterol (0.8-100 μg/mL; 24 h) completely disrupts mature Pseudomonas aeruginosa biofilms at 1.6 μg/mL, and causes significant disruption at all tested concentrations up to 100 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 481-17-4
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분자량 412.70
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화학식 C29H48O
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SMILES
C[C@@]12[C@](C=3[C@@]([C@]4(C)[C@@](CC3)(C[C@@H](O)CC4)[H])(CC1)[H])(CC[C@@]2([C@@H](/C=C/[C@@H](C(C)C)CC)C)[H])[H]
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)