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United States

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Cat. No.: HY-172745

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Conglobatin B1

Conglobatin B1 is a compound that can be isolated from Australian Streptomyces MST-91080. Conglobatin B1 is cytotoxic to the NS-1 myeloma cell line with an IC₅₀ of 0.084 μg/mL, but has low toxicity to NFF human fibroblasts. Conglobatin B1 can be used in the study of cancer.

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CAS No.: 3053775-15-5
화학식: C₂₇H₃₆N₂O₆
분자량:484.58

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Conglobatin B1 Chemical Structure

CAS No.: 3053775-15-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

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Chemical Information

CAS No. 3053775-15-5
분자량 484.58
화학식 C₂₇H₃₆N₂O₆
SMILES

C[C@@H](C[C@H](/C=C(C(O[C@H]([C@H](CC/C=C(C(O1)=O)\C)C)CC2=CN=CO2)=O)\C)C)[C@@H]1CC3=CN=CO3
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lacey HJ, et al. Conglobatins B-E: cytotoxic analogues of the C2-symmetric macrodiolide conglobatin. J Antibiot (Tokyo). 2020 Nov;73(11):756-765. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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