COTC
COTC is a bacterial metabolite with anticancer activity that is found in S. griseosporeus. COTC inhibits glyoxalase in the presence of glutathione (GSH). COTC also inhibits the proliferation of HeLa cells (IC50 = 18 µg/mL), as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model.
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- CAS No.: 57449-30-6
- 화학식: C11H14O6
- 분자량:242.23
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보관:
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Biological Activity
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 57449-30-6
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분자량 242.23
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화학식 C11H14O6
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SMILES
C/C=C/C(OCC1=C[C@@H](O)[C@@H](O)[C@@H](O)C1=O)=O
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Structure Classification
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Initial Source
Streptomyces griseosporeus
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COTC Related Classifications
HY-N12255 Related Classifications
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