CP 81282
CP 81282 is a tripeptide aspartic protease inhibitor, with an IC50 of 1 nM against human renin and an IC50 of 11 nM against endopeptidase. CP 81282 is applicable to the research of hypertension.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 121584-61-0
- 화학식: C32H47F2N5O6
- 분자량:635.74
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
CP 81282 potently inhibits human plasma renin with an IC50 of 1 nM and endothiapepsin with an IC50 of 11 nM[1].
CP 81282 binds to endothiapepsin as a tetrahedral hydrate, forming specific hydrogen bonds with active-site aspartates 32 and 215, and adopts an extended conformation that interacts with additional enzyme residues[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 121584-61-0
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분자량 635.74
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화학식 C32H47F2N5O6
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SMILES
CNC(C(F)(C(C(NC(C(NC(C(CC1=CC=CC=C1)NC(N2CCOCC2)=O)=O)CCCC)=O)CC3CCCCC3)=O)F)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CP 81282 Related Classifications
HY-117641 Related Classifications
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