CypD-IN-4
CypD-IN-4 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-4 has CypD affinity with an IC50 value of 0.057 μM. CypD-IN-4 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes.
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- CAS No.: 3023438-19-6
- 화학식: C54H63N7O11
- 분자량:986.12
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
All Cyclophilin Isoforms
More
Biological Activity
제품 설명
IC50 & Target
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Cyclophilin D 0.057 μM (IC50) |
Cyclophilin A 3.4 μM (IC50) |
Cyclophilin B 1.1 μM (IC50) |
Cyclophilin E 0.8 μM (IC50) |
In Vitro
CypD-IN-4 (B53) has selectivity for inhibiting CypD, CypA, CypB and CypE with IC50 values of 0.057 μM, 3.4 μM, 1.1 μM and 0.8 μM, respectively[1].
CypD-IN-4 (20 μM) inhibits mitochondrial permeability transition pore opening in isolated mitochondria[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3023438-19-6
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분자량 986.12
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화학식 C54H63N7O11
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SMILES
NCCOCCNC([C@@H]1CCNC(/C=C/C(N2CCC[C@](C2)(C(N[C@H](C(NCC3=C(CC(N1)=O)C=CC=C3)=O)CC4=CC=C(C=C4)C5=CC=C(C=C5)C(CC(O)=O)CC(O)=O)=O)CC6=CC=CC=C6)=O)=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CypD-IN-4 Related Classifications
HY-151488 Related Classifications
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