DBCO-PEG3-amine
DBCO-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG3-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- CAS No.: 2093409-57-3
- 화학식: C27H33N3O5
- 분자량:479.57
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보관:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
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Mal-PEG2-acidADC Linker -
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Biotin-PEG3-azidePROTAC Linker -
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DBCO-PEG4-C2-acidPROTAC Linker -
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N3-PEG4-C2-NH2PROTAC Linkers -
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Hydroxy-PEG2-(CH2)2-BocADC Linker
All PROTAC Linkers Isoforms
More
Biological Activity
제품 설명
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2093409-57-3
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Appearance Solid
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분자량 479.57
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화학식 C27H33N3O5
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Color Off-white to light yellow
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SMILES
NCCOCCOCCOCCNC(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
순도&문서
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Data Sheet (265 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DBCO-PEG3-amine Related Classifications
HY-134714 Related Classifications
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