DBM-MMAF
Based on 2 publication(s) in Google Scholar
DBM-MMAF is a agent-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody agent conjugate (ADC).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.65%
- CAS No.: 1810001-93-4
- 화학식: C49H74Br2N6O11
- 분자량:1082.95
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) DBM-MMAF
MoreAll Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
제품 설명
IC50 & Target
[1]|
Auristatin |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1810001-93-4
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Appearance Solid
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분자량 1082.95
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화학식 C49H74Br2N6O11
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Color Off-white to light yellow
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SMILES
C[C@@H](C(N[C@H](C(O)=O)CC1=CC=CC=C1)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(CCCCCN(C3=O)C(C(Br)=C3Br)=O)=O)=O)=O)=O)OC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Cells
2023 Sep 30;12(19):2393. PMID: 37830607
용액&용해도
In Vitro:
DMSO : 200 mg/mL (184.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9234 mL | 4.6170 mL | 9.2340 mL | 23.0851 mL |
| 5 mM | 0.1847 mL | 0.9234 mL | 1.8468 mL | 4.6170 mL | |
| 10 mM | 0.0923 mL | 0.4617 mL | 0.9234 mL | 2.3085 mL | |
| 15 mM | 0.0616 mL | 0.3078 mL | 0.6156 mL | 1.5390 mL | |
| 20 mM | 0.0462 mL | 0.2309 mL | 0.4617 mL | 1.1543 mL | |
| 25 mM | 0.0369 mL | 0.1847 mL | 0.3694 mL | 0.9234 mL | |
| 30 mM | 0.0308 mL | 0.1539 mL | 0.3078 mL | 0.7695 mL | |
| 40 mM | 0.0231 mL | 0.1154 mL | 0.2309 mL | 0.5771 mL | |
| 50 mM | 0.0185 mL | 0.0923 mL | 0.1847 mL | 0.4617 mL | |
| 60 mM | 0.0154 mL | 0.0770 mL | 0.1539 mL | 0.3848 mL | |
| 80 mM | 0.0115 mL | 0.0577 mL | 0.1154 mL | 0.2886 mL | |
| 100 mM | 0.0092 mL | 0.0462 mL | 0.0923 mL | 0.2309 mL |
DBM-MMAF Related Classifications
HY-136287 Related Classifications
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