Deschlorodiazepam
Based on 1 Customer Validation
Deschlorodiazepam is an analytical reference standard categorized as a benzodiazepine.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.64%
- CAS No.: 3034-65-9
- 화학식: C16H14N2O
- 분자량:250.30
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보관:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
>10 μM
Compound: figure 3, R4C1
|
Displacement of [3H]Ro15-4513 from GABAA alpha-1-beta-2-gamma-2 receptor expressed in Sf9 baculovirus system
Displacement of [3H]Ro15-4513 from GABAA alpha-1-beta-2-gamma-2 receptor expressed in Sf9 baculovirus system
|
[PMID: 18537233] |
| Sf9 | IC50 |
>10 μM
Compound: figure 3, R4C1
|
Displacement of [3H]Ro15-4513 from GABAA alpha-5-beta-2-gamma-2 receptor expressed in Sf9 baculovirus system
Displacement of [3H]Ro15-4513 from GABAA alpha-5-beta-2-gamma-2 receptor expressed in Sf9 baculovirus system
|
[PMID: 18537233] |
Chemical Information
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CAS No. 3034-65-9
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Appearance Solid
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분자량 250.30
-
화학식 C16H14N2O
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Color Light yellow to brown
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SMILES
O=C1N(C)C2=C(C(C3=CC=CC=C3)=NC1)C=CC=C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
용액&용해도
DMSO : 25 mg/mL (99.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Basile AS, et al. Brain concentrations of benzodiazepines are elevated in an animal model of hepatic encephalopathy. Proc Natl Acad Sci U S A. 1990 Jul;87(14):5263-7. [Content Brief]
[2]. Sternbach LH, et al. Quinazolines and 1,4-benzodiazepines. 64. Comparison of the stereochemistry of diazepam with that of close analogs with marginal biological activity. J Med Chem. 1974 Mar;17(3):374-7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9952 mL | 19.9760 mL | 39.9521 mL | 99.8801 mL |
| 5 mM | 0.7990 mL | 3.9952 mL | 7.9904 mL | 19.9760 mL | |
| 10 mM | 0.3995 mL | 1.9976 mL | 3.9952 mL | 9.9880 mL | |
| 15 mM | 0.2663 mL | 1.3317 mL | 2.6635 mL | 6.6587 mL | |
| 20 mM | 0.1998 mL | 0.9988 mL | 1.9976 mL | 4.9940 mL | |
| 25 mM | 0.1598 mL | 0.7990 mL | 1.5981 mL | 3.9952 mL | |
| 30 mM | 0.1332 mL | 0.6659 mL | 1.3317 mL | 3.3293 mL | |
| 40 mM | 0.0999 mL | 0.4994 mL | 0.9988 mL | 2.4970 mL | |
| 50 mM | 0.0799 mL | 0.3995 mL | 0.7990 mL | 1.9976 mL | |
| 60 mM | 0.0666 mL | 0.3329 mL | 0.6659 mL | 1.6647 mL | |
| 80 mM | 0.0499 mL | 0.2497 mL | 0.4994 mL | 1.2485 mL |