DNDI-6510
DNDI-6510 (Compound (S)-x38) is a non-covalent SARS-CoV-2 MPro inhibitor with a IC50 of 0.04 μM. DNDI-6510 has a potent antiviral activity across SARS-CoV-2 and its variants as well as a weak efficacy to SARS-CoV-1. DNDI-6510 significantly improves drug exposure in metabolically humanized mice model (8HUM).
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- 화학식: C26H23ClN4O3
- 분자량:474.94
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
IC50 & Target
[1]|
CYP3A4 |
CYP2C8 |
CYP2C9 |
CYP2C19 |
CYP2D6 |
Chemical Information
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분자량 474.94
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화학식 C26H23ClN4O3
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SMILES
CNC(C1(CC1)N2C[C@@]3(C4=C(C2=O)C=CC(Cl)=C4)CCN(C3=O)C5=C6C=CC=CC6=CN=C5)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)