EP055
EP055 is a non-hormonal male contraceptive. EP055 targets to sperm protein EPPIN and inhibits anti-EPPIN antibodies from binding EPPIN with an IC50 of 1121 μM. EP055 can inhibit sperm motility (IC50 = 199.5 μM) by reducing the internal pH and Ca2+ levels of the sperm, thereby causing the sperm to aggregate. EP055 can be used for development of male contraceptive.
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- CAS No.: 2411173-40-3
- 화학식: C15H17N7O6S
- 분자량:423.40
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Spermatozoa | IC50 |
200 μM
Compound: EP055
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Inhibition of sperm motility in human Spermatozoa incubated for 1 to 2 hrs by computer assisted sperm analysis
Inhibition of sperm motility in human Spermatozoa incubated for 1 to 2 hrs by computer assisted sperm analysis
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[PMID: 36087385] |
Chemical Information
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CAS No. 2411173-40-3
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분자량 423.40
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화학식 C15H17N7O6S
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SMILES
O=C(CSC1=NC(NC2=CC=C(C(O)=C2)NC(C)=O)=NC(NNC(OC)=O)=N1)O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EP055 Related Classifications
HY-171129 Related Classifications
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