Etaconazol
Etaconazol (Etaconazole) is an azole fungicide. Etaconazol possesses endocrine-disrupting potential and inhibits placental steroidogenesis by suppressing 3β-hydroxysteroid dehydrogenase (3β-HSD1). Etaconazol binds to the NAD+/steroid-binding site of the target enzyme and acts on both the free enzyme and enzyme-substrate complex to inhibit their activity.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 60207-93-4
- 화학식: C14H15Cl2N3O2
- 분자량:328.19
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
Etaconazole (0-100 μM; 30 min) potently inhibits the activity of human placental microsomal 3β-HSD1, with an IC50 of 78 μM and a Ki of 88.9 μM[1].
Etaconazole (0-100 μM; 30 min) inhibits 3β-HSD4 activity in rat placental microsomes, with an IC50 of 102.6 μM and a Ki of 109.6 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 60207-93-4
-
분자량 328.19
-
화학식 C14H15Cl2N3O2
-
SMILES
ClC1=CC=C(C(Cl)=C1)C2(OCC(O2)CC)CN3N=CN=C3
-
Synonyms
Etaconazole
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Etaconazol Related Classifications
HY-W714186 Related Classifications
Powered by Bioz