Fatostatin hydrobromide

(Synonyms: 125B11 hydrobromide)
56 Cited Publications
고객리뷰

Based on 56 publication(s) in Google Scholar

Fatostatin hydrobromide (125B11 hydrobromide), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin hydrobromide binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin hydrobromide decreases the transcription of lipogenic genes in cells. Fatostatin hydrobromide possesses antitumor properties, and lowers hyperglycemia in ob/ob mice.

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  • Purity: 99.52%
  • CAS No.: 298197-04-3
  • 화학식: C18H19BrN2S
  • 분자량:375.33
  • 보관:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

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