Fluoxastrobin
Fluoxastrobin is a fungicide. By binding to NAD-dependent epimerase/dehydratase, Fluoxastrobin interferes with electron transport, reduces ATP production and inhibits mycelial growth, thereby effectively controlling foliar diseases of tea plants. Fluoxastrobin induces oxidative stress by increasing ROS levels and lipid peroxidation, causes DNA damage and promotes apoptosis; meanwhile, it shows high acute toxicity to Danio rerio embryos and larvae. Fluoxastrobin can be used in research related to tea foliar diseases (including tea red leaf spot and tea gray leaf spot).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 361377-29-9
- 화학식: C21H16ClFN4O5
- 분자량:458.83
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
More
Biological Activity
제품 설명
In Vitro
Fluoxastrobin (13.64 μg/mL) inhibits Pestalotiopsis trachicarpicola hyphal growth with an in vitro half-maximal effective concentration of 13.64 μg/mL, disrupts fungal energy metabolism via dose-dependent inhibition of ATP production and elevation of hyphal membrane potential, and binds stably to the fungal NAD-dependent epimerase/dehydratase[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
- Detection of Apoptosis
- TUNEL staining for apoptotic DNA fragmentation
- Annexin V plus membrane-impermeant dye apoptosis staining
- ROS/oxidative-stress fluorescent staining
- Apoptosis Solutions
- Filamentous Fungal Mold Culture and Sporulation
- Ferroptosis Solutions
- Genotoxicity/Mutagenicity Study
- Acute Systemic Toxicity Study
Chemical Information
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CAS No. 361377-29-9
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분자량 458.83
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화학식 C21H16ClFN4O5
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SMILES
C(=N\OC)(\C1=C(OC=2C(F)=C(OC3=C(Cl)C=CC=C3)N=CN2)C=CC=C1)/C4=NOCCO4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Fluoxastrobin Related Classifications
HY-W008927 Related Classifications
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Keywords
- Fluoxastrobin
- 361377-29-9
- Fungal
- Reactive Oxygen Species (ROS)
- DNA/RNA Synthesis
- Apoptosis
- *Pestalotiopsis trachicarpicola*
- superoxide dismutase
- gray blight
- phytopathogenic fungi
- glutathione peroxidase
- tea leaf spot
- *Danio rerio*
- tea foliar disease pathogens
- NAD-dependent epimerase/dehydratase
- catalase
- Inhibitor
- inhibitor
- inhibit