Human UGT2B17
Based on 1 Customer Validation
Human UGT2B17 is a UDP-glucuronosyltransferase. Human UGT2B17 catalyzes the glucuronidation of Testosterone at the 17β-OH position, binds Epitestosteron with comparable affinity, but cannot catalyze its glucuronidation.
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
IC50 & Target
[1]|
UGT2B17 |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Human UGT2B17]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
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Data Sheet (263 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Sten T, et al. UDP-glucuronosyltransferases (UGTs) 2B7 and UGT2B17 display converse specificity in testosterone and epitestosterone glucuronidation, whereas UGT2A1 conjugates both androgens similarly. Drug Metab Dispos. 2009 Feb;37(2):417-23. [Content Brief]
[2]. Strahm E, et al. Implication of Human UGT2B7, 2B15, and 2B17 in 19-Norandrosterone Metabolism. Frontiers in endocrinology. 2013;4:75. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)