Hydantoin
Based on 1 Customer Validation
Hydantoin is an imidazolidine-2,4-dione and serves as the parent nucleus of the antiepileptic agent Phenytoin (HY-B0448).
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- CAS No.: 461-72-3
- 화학식: C3H4N2O2
- 분자량:100.08
-
보관:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MRC5 | IC50 |
>100 μM
Compound: 1a
|
Cytotoxicity against human MRC5 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
Cytotoxicity against human MRC5 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
|
[PMID: 38484804] |
| MRC5 | IC50 |
100 μM
Compound: 1a
|
Cytotoxicity against human MRC5 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
Cytotoxicity against human MRC5 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
|
[PMID: 38484804] |
Hydantoin moieties in crystallized derivatives exhibit diverse hydrogen-bonding networks, with the centrosymmetric chain-of-rings arrangement observed in 10% of the studied structures, and the less-charged O4 atom frequently unused in hydrogen bonding[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 461-72-3
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Appearance Solid
-
분자량 100.08
-
화학식 C3H4N2O2
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Color White to off-white
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SMILES
O=C1NC(=O)CN1
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
순도&문서
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)