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Cat. No.: HY-A0160

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Indalpine

Name: Indalpine
Brand: MedChemExpress
SKU: HY-A0160
Availability: PreOrder

(Synonyms: LM 5008)

Indalpine (LM 5008) is a potent and selective 5-HT uptake blocker. Indalpine is potent in displacing ³H-5-HT bound to brain membranes with the IC₅₀ of 36 μM. Indalpine, two antidepressant agent.

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CAS No.: 63758-79-2
화학식: C₁₅H₂₀N₂
분자량:228.33

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Indalpine Chemical Structure

CAS No.: 63758-79-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Indalpine (LM 5008) is a potent and selective 5-HT uptake blocker. Indalpine is potent in displacing ³H-5-HT bound to brain membranes with the IC₅₀ of 36 μM^[1]. Indalpine, two antidepressant agent^[2].

In Vivo

In keeping with its potent reuptake-blocking property, acute IV Indalpine produces a marked decrease in the firing rate of dorsal raphe 5-HT neurons (ED50 0.33 mg/kg). The firing rate of dorsal raphe 5-HT neurons is assessed following 2-, 7- and 14-day treatments with Indalpine (5 mg/day IP). After 2 days, the firing rate of 5-HT neurons is greatly reduced, after 7 days it has recovered partially and after 14 days it has returned to normal^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 63758-79-2
분자량 228.33
화학식 C₁₅H₂₀N₂
SMILES

C1(CCC2CCNCC2)=CNC3=C1C=CC=C3
Synonyms

LM 5008
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. R Samanin, et al. Further studies on the mechanism of serotonin-dependent anorexia in rats. Psychopharmacology (Berl). 1980;68(1):99-104. [Content Brief]

[2]. P Blier, et al. Effects of the two antidepressant drugs mianserin and Indalpine on the serotonergic system: single-cell studies in the rat. Psychopharmacology (Berl). 1984;84(2):242-9. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- In Vivo
Chemical Information
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Indalpine

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Dapoxetine hydrochloride

ZZL-7

Venlafaxine hydrochloride (Standard)

Adoxosidic acid

Citalopram-d4 hydrobromide

(S)-Venlafaxine

Ampreloxetine hydrochloride

Duloxetine-d7

Duloxetine hydrochloride (Standard)

Biological Activity

Chemical Information

순도&문서

References

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Bioz

Indalpine

Duloxetine hydrochloride

Venlafaxine hydrochloride

Fluvoxamine maleate

Dapoxetine hydrochloride

ZZL-7

Venlafaxine hydrochloride (Standard)

Adoxosidic acid

Citalopram-d4 hydrobromide

(S)-Venlafaxine

Ampreloxetine hydrochloride

Duloxetine-d7

Duloxetine hydrochloride (Standard)

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Indalpine Related Classifications

HY-A0160 Related Classifications

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