IP6K2-IN-1
Based on 1 Customer Validation
IP6K2-IN-1 is a selective flavonoid-based IP6K2 inhibitor with an IC50 value of 0.55 μM. IP6K2-IN-1 shows higher inhibitory potency against IP6K2 than IP6K1 and IP6K3. IP6K2-IN-1 can be utilised as a hit compound for further structural modifications of IP6K2 inhibitors.
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- Purity: 99.47%
- CAS No.: 2926679-10-7
- 화학식: C16H10O7
- 분자량:314.25
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보관:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
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IP6K2 |
IP6K2-IN-1 (Compound 20s) shows IC50 value of 2.87 µM against IP6K1 resulting 5.22-fold IC50 ratio of IP6K1/IP6K2 and IC50 value of 3.56 µM against IP6K3, resulting 6.47-fold IC50 ratio of IP6K3/IP6K2[1].
IP6K2-IN-1 failed to reduce IP7 levels in HCT116 cells, indicating low cell permeability[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2926679-10-7
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Appearance Solid
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분자량 314.25
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화학식 C16H10O7
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Color Yellow to brown
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SMILES
OC1=C(O)C=C(C(C(O)=C(C2=CC(C(O)=O)=CC=C2)O3)=O)C3=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
순도&문서
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)