Jun13296
Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 µM, Ki = 8.8 nM). Jun13296 exhibits potent inhibition against SARS-CoV-2 variants and Nirmatrelvir (HY-138687)-resistant mutants. Jun13296 improves lung viral titers, and prevents lung tissue damage in a SARS-CoV-2 infection model.
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- CAS No.: 3063566-68-4
- 화학식: C30H34N6O
- 분자량:494.63
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 µM, Ki = 8.8 nM)
Chemical Information
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CAS No. 3063566-68-4
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분자량 494.63
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화학식 C30H34N6O
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SMILES
O=C(N[C@@H](C1=CC(C2=CN(C)N=C2)=NC3=CC=CC=C13)C)C4=CC(N5C[C@@](N6C)([H])CC[C@@]6([H])C5)=CC=C4C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Jun13296 Related Classifications
HY-168916 Related Classifications
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