L-739943
L-739943 is a potent, and orally active growth hormone (GH) secretagogue with an ED50 of 1 nM. L-739943 stimulates GH release in beagle dogs. L-739943 can be used for GH-related diseases research.
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- CAS No.: 195248-02-3
- 화학식: C30H36ClN5O3
- 분자량:550.09
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Chemical Information
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CAS No. 195248-02-3
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분자량 550.09
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화학식 C30H36ClN5O3
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SMILES
CC(C)(N)C(N[C@@H](C1=O)CCC2=CC=CC=C2N1CC3=CC=C(C4=C(C=CC=C4)CNC(NC)=O)C=C3)=O.Cl
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)