Lepidozin G
Lepidozin G inhibits the growth of a panel of cancer cell lines with IC50 values ranging from 4.2 ± 0.2 to 5.7 ± 0.5 μM. Lepidozin G induces PC-3 cell death via mitochondrial-related apoptosis.
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- CAS No.: 2869125-43-7
- 화학식: C30H48O4
- 분자량:472.70
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
4.4 μM
Compound: 7
|
Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 34797067] |
| NCI-H3255 | IC50 |
5.7 μM
Compound: 7
|
Cytotoxicity against human NCI-H3255 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-H3255 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 34797067] |
| NCI-H446 | IC50 |
5 μM
Compound: 7
|
Cytotoxicity against human NCI-H446 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-H446 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 34797067] |
| PC-3 | IC50 |
4.2 μM
Compound: 7
|
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 34797067] |
Chemical Information
-
CAS No. 2869125-43-7
-
분자량 472.70
-
화학식 C30H48O4
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SMILES
CC(C(CC[C@@H](C)[C@@]1([H])[C@H](O)C[C@@]2(C)[C@]3([H])CC[C@]4([H])[C@@](CC[C@H](O)C4(C)C)(O)CC3=CC[C@@]21C)=O)=C
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)