m-PEG4-PFP ester
Based on 1 Customer Validation
m-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.0%
- CAS No.: 2952895-31-5
- 화학식: C16H19F5O6
- 분자량:402.31
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보관:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2952895-31-5
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Appearance Liquid (Density: 1.316±0.06 g/cm3)
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분자량 402.31
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화학식 C16H19F5O6
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Color Colorless to light yellow
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SMILES
COCCOCCOCCOCCC(OC1=C(F)C(F)=C(F)C(F)=C1F)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : ≥ 100 mg/mL (248.56 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4856 mL | 12.4282 mL | 24.8565 mL | 62.1411 mL |
| 5 mM | 0.4971 mL | 2.4856 mL | 4.9713 mL | 12.4282 mL | |
| 10 mM | 0.2486 mL | 1.2428 mL | 2.4856 mL | 6.2141 mL | |
| 15 mM | 0.1657 mL | 0.8285 mL | 1.6571 mL | 4.1427 mL | |
| 20 mM | 0.1243 mL | 0.6214 mL | 1.2428 mL | 3.1071 mL | |
| 25 mM | 0.0994 mL | 0.4971 mL | 0.9943 mL | 2.4856 mL | |
| 30 mM | 0.0829 mL | 0.4143 mL | 0.8285 mL | 2.0714 mL | |
| 40 mM | 0.0621 mL | 0.3107 mL | 0.6214 mL | 1.5535 mL | |
| 50 mM | 0.0497 mL | 0.2486 mL | 0.4971 mL | 1.2428 mL | |
| 60 mM | 0.0414 mL | 0.2071 mL | 0.4143 mL | 1.0357 mL | |
| 80 mM | 0.0311 mL | 0.1554 mL | 0.3107 mL | 0.7768 mL | |
| 100 mM | 0.0249 mL | 0.1243 mL | 0.2486 mL | 0.6214 mL |
m-PEG4-PFP ester Related Classifications
HY-138382 Related Classifications
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