Matricarin
Matricarin is a sesquiterpene lactone antioxidant with ferric ion reducing antioxidant power activity. Matricarin exhibits free radical scavenging activity. Matricarin induces growth inhibition. Matricarin can be used in the research of ovarian cancer and renal cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 5989-43-5
- 화학식: C17H20O5
- 분자량:304.34
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
100 μM
Compound: 8
|
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production by Griess reagent based spectrophotometric analysis
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production by Griess reagent based spectrophotometric analysis
|
[PMID: 29122483] |
In Vitro
Matricarin is a compound isolated from the leaves of the Artemisia tridentata tridentata subspecies, and its ferric reducing antioxidant activity is 13.22 µM TE/g FW[1].
Matricarin (10-5 M) achieves a growth inhibition rate of up to 89% in OVCAR-3 ovarian cancer cells and a lethality rate of 28% in A498 renal cancer cells, but its overall anti-tumor activity in the NCI-60 cell panel is not significant[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 5989-43-5
-
분자량 304.34
-
화학식 C17H20O5
-
SMILES
CC([C@]1([H])[C@]2([H])[C@@]([C@@H](C(O2)=O)C)([H])[C@H](CC(C)=C13)OC(C)=O)=CC3=O
-
Structure Classification
-
Initial Source
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Matricarin
- 5989-43-5
- Biochemical Assay Reagents
- radical-scavenging capacity
- OVCAR-3 ovarian cancer cells
- antioxidant
- ferric reducing antioxidant power
- A498 renal cancer cells
- Artemisia tridentata subsp. tridentata
- renal cancer
- ovarian cancer
- NCI-60 cancer cell line
- sesquiterpene lactone
- Inhibitor
- inhibitor
- inhibit