(-)-Conocarpan
(-)-Conocarpan is a natural compound that can be isolated from various species of Krarneria.
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- CAS No.: 56319-02-9
- 화학식: C18H18O2
- 분자량:266.33
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
19.5 μM
Compound: 7
|
Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before addition of PGH2 by RP-HPLC method
Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before addition of PGH2 by RP-HPLC method
|
[PMID: 21800856] |
| HEK293 | IC50 |
>20 μM
Compound: 7
|
Inhibition of NFkappaB activity transfected in HEK293 cells pretreated for 1 hr before 6 hrs of LPS challenge by luciferase reporter gene assay
Inhibition of NFkappaB activity transfected in HEK293 cells pretreated for 1 hr before 6 hrs of LPS challenge by luciferase reporter gene assay
|
[PMID: 21800856] |
Chemical Information
-
CAS No. 56319-02-9
-
분자량 266.33
-
화학식 C18H18O2
-
SMILES
OC1=CC=C([C@@H]2OC3=CC=C(/C=C/C)C=C3[C@H]2C)C=C1
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)