Mitapivat-d8
Mitapivat-d8 (AG-348-d8) is the deuterium labeled Mitapivat (HY-12689). Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency.
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- 화학식: C24H18D8N4O3S
- 분자량:458.60
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 1260075-17-9
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분자량 458.60
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화학식 C24H18D8N4O3S
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SMILES
O=S(C1=C2N=CC=CC2=CC=C1)(NC3=CC=C(C(N4C([2H])([2H])C([2H])([2H])N(CC5CC5)C([2H])([2H])C4([2H])[2H])=O)C=C3)=O
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Synonyms
AG-348-d8
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mitapivat-d8 Related Classifications
HY-12689S Related Classifications
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