MK-4688
MK-4688 is an efficient inhibitor of the HDM2-p53 protein-protein interaction.
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- CAS No.: 1616428-79-5
- 화학식: C28H32ClN7O3
- 분자량:550.05
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
122 nM
Compound: 56; MK-4688
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Antiproliferative activity against human HCT-116 cells expressing wild-type p53 incubated for 72 hrs
Antiproliferative activity against human HCT-116 cells expressing wild-type p53 incubated for 72 hrs
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[PMID: 34714078] |
Chemical Information
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CAS No. 1616428-79-5
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분자량 550.05
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화학식 C28H32ClN7O3
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SMILES
C[C@@H](CC1)CC[C@H]1CN(C(N2CCO[C@H]3[C@H]2CCC3)=N4)C5=C4C=C(C(N6)=NOC6=O)N=C5C7=CC(Cl)=CN=C7
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MK-4688 Related Classifications
HY-139846 Related Classifications
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