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Cat. No.: HY-146651

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MPO-IN-4

MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC₅₀0 of 25 nM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2088545-68-8
화학식: C₁₂H₁₁N₅
분자량:225.25

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

MPO-IN-4 Chemical Structure

CAS No.: 2088545-68-8

사이즈

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC₅₀0 of 25 nM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT)^[1].

All Glutathione Peroxidase Isoforms :

GPX1
GPX4

Chemical Information

CAS No. 2088545-68-8
분자량 225.25
화학식 C₁₂H₁₁N₅
SMILES

NC1=CC(CC2=CC=CC=C2)=C3N=NNC3=N1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Scott A Shaw, et al. Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase. Bioorg Med Chem. 2020 Nov 15;28(22):115723. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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MPO-IN-4

All Glutathione Peroxidase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

MPO-IN-4 Related Classifications

HY-146651 Related Classifications