Nafenodone
Nafenodone is an antidepressant agent. Nafenodone can reduce the rate and amplitude of contractions and lengthen sinus node recovery time. Nafenodone can inhibit the spontaneous mechanical activity in portal vein segmens with an IC50 of 1.4 μM in rat isolated vascular smooth muscle. Nafenodone relaxes the contractions induced by high K+ and noradrenaline.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 92615-20-8
- 화학식: C20H23NO
- 분자량:293.40
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 92615-20-8
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분자량 293.40
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화학식 C20H23NO
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SMILES
O=C1C2=C(CCC1(CCN(C)C)C3=CC=CC=C3)C=CC=C2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Pérez-Vizcaino, F., et al., (1991). Effects of (S)-nafenodone, a new antidepressant, in isolated guinea-pig atrial and ventricular muscle fibres. European journal of pharmacology, 199(1), 43-50. [Content Brief]
[2]. Pérez-Vizcaíno, F., et al., (1993). Effects of (S)-nafenodone on 45Ca2+ fluxes and contractions in rat isolated vascular smooth muscle. European journal of pharmacology, 232(1), 105-111. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)