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Cat. No.: HY-180321

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OAT-1441

OAT-1441 is a selective hAMCase inhibitor with oral activity (IC₅₀ = 7 nM). OAT-1441 can be used to study the physiological functions of hAMC enzymes.

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CAS No.: 2088453-79-4
화학식: C₂₃H₂₇ClN₆O
분자량:438.96

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

OAT-1441 Chemical Structure

CAS No.: 2088453-79-4

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

OAT-1441 is a selective hAMCase inhibitor with oral activity (IC₅₀ = 7 nM). OAT-1441 can be used to study the physiological functions of hAMC enzymes^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CHO-K1	IC₅₀	23000 nM Compound: 11; OAT-1441	Inhibition of human ERG expressed in CHO-K1 cells by automated Qpatch-clamp assay Inhibition of human ERG expressed in CHO-K1 cells by automated Qpatch-clamp assay	[PMID: 32551005]

Chemical Information

CAS No. 2088453-79-4
분자량 438.96
화학식 C₂₃H₂₇ClN₆O
SMILES

C([C@@H]1N(CC=2C(OC1)=CC=CC2)C3CCN(CC3)C=4NC(N)=NN4)C5=CC=C(Cl)C=C5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Andryianau G,et al. Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase. ACS Med Chem Lett. 2020 Apr 24;11(6):1228-1235. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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